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Case Studies

Neural Sensor Development

SB Microsystems-productsSBM has developed a microscale, lithographically defined silicon microprobe for continuous in vivo measurements of neuronal activity in the central nervous systems of a variety of laboratory animals and primates.

Diagnostic Biochips Inc (DBC): Between 2006 and 2013, SBM developed a microscale, lithographically defined silicon microprobe for continuous in vivo measurements of neuronal activity in the central nervous systems of a variety of laboratory animals including rodents (rats and mice), insects (fruit flies and dragonflies), zebra fish, and primates. During this time, dozens of laboratories have utilized our technology, generating a trove of fundamental neuroscience data that is being presented in a variety of scientific journals. This approach is at the forefront of the NIH “BRAIN” initiative to fund and develop methods for mapping neuronal circuitry. The pre-clinical market for this product is estimated to be in the range of $10M-$50M annually, and in 2013 DBC was created to market and sell the device. This technology has been licensed to DBC, and the devices are being distributed through a third party instrument reseller based in the UK. DBC has also entered into a supplier agreement with Howard Hughes Medical Institute, who was an early funding source for this technology. SBM continues to develop additional IP related to this project, including technology that will convert the sensing sites from detectors of neuronal activity to highly selective chemical sensors capable of continuously measuring a wide variety of chemical analytes

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